InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ncam1

Summary

InnateDB Gene

IDBG-163105.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ncam1

Gene Name

neural cell adhesion molecule 1

Synonyms

CD56; E-NCAM; Ncam; NCAM-1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000039542

Encoded Proteins

IDBP-251668

neural cell adhesion molecule 1

IDBP-622811

neural cell adhesion molecule 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149294:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:49504361-49798922

Strand

Reverse strand

Band

A5.3

Transcripts

ENSMUST00000114476	ENSMUSP00000110120
ENSMUST00000166811	ENSMUSP00000130668

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001928	regulation of exocyst assembly
GO:0007166	cell surface receptor signaling pathway
GO:0031175	neuron projection development
GO:0034109	homotypic cell-cell adhesion
GO:0050850	positive regulation of calcium-mediated signaling