Mus musculus Gene: Ncam1
Summary
InnateDB Gene IDBG-163105.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ncam1
Gene Name neural cell adhesion molecule 1
Synonyms CD56; E-NCAM; Ncam; NCAM-1;
Species Mus musculus
Ensembl Gene ENSMUSG00000039542
Encoded Proteins
neural cell adhesion molecule 1
neural cell adhesion molecule 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149294:
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:49504361-49798922
Strand Reverse strand
Band A5.3
Transcripts
ENSMUST00000114476 ENSMUSP00000110120
ENSMUST00000166811 ENSMUSP00000130668
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001928 regulation of exocyst assembly
GO:0007166 cell surface receptor signaling pathway
GO:0031175 neuron projection development
GO:0034109 homotypic cell-cell adhesion
GO:0050850 positive regulation of calcium-mediated signaling
Cellular Component
GO:0005911 cell-cell junction
GO:0009897 external side of plasma membrane
GO:0030424 axon
GO:0030426 growth cone
GO:0043025 neuronal cell body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Cell adhesion molecules (CAMs) pathway
Prion diseases pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Developmental Biology pathway
Extracellular matrix organization pathway
NCAM signaling for neurite out-growth pathway
Cytokine Signaling in Immune system pathway
NCAM1 interactions pathway
Axon guidance pathway
Interferon Signaling pathway
Immune System pathway
ECM proteoglycans pathway
Interferon gamma signaling pathway
L1CAM interactions pathway
Signal transduction by L1 pathway
KEGG
Cell adhesion molecules (CAMs) pathway
Prion diseases pathway
INOH
PID BIOCARTA
PID NCI
FGF signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001081445 NM_001113204 NM_010875 XM_006510072
OMIM
CCDS CCDS40617 CCDS40618
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas