Homo sapiens Gene: CAMK1
Summary
InnateDB Gene IDBG-16330.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAMK1
Gene Name calcium/calmodulin-dependent protein kinase I
Synonyms CAMKI;
Species Homo sapiens
Ensembl Gene ENSG00000134072
Encoded Proteins
calcium/calmodulin-dependent protein kinase I
calcium/calmodulin-dependent protein kinase I
calcium/calmodulin-dependent protein kinase I
calcium/calmodulin-dependent protein kinase I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008]
Calcium/calmodulin-dependent protein kinase I is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:9757342-9769992
Strand Reverse strand
Band p25.3
Transcripts
ENST00000256460 ENSP00000256460
ENST00000397277 ENSP00000380447
ENST00000421120 ENSP00000393238
ENST00000411972 ENSP00000404587
ENST00000496534
ENST00000482803
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004683 calmodulin-dependent protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006468 protein phosphorylation
GO:0006913 nucleocytoplasmic transport
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0010976 positive regulation of neuron projection development
GO:0032880 regulation of protein localization
GO:0043393 regulation of protein binding
GO:0046827 positive regulation of protein export from nucleus
GO:0051147 regulation of muscle cell differentiation
GO:0051149 positive regulation of muscle cell differentiation
GO:0051835 positive regulation of synapse structural plasticity
GO:0060999 positive regulation of dendritic spine development
GO:0071902 positive regulation of protein serine/threonine kinase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL F8W6S9
UniProt Splice Variant
Entrez Gene 8536
UniGene
RefSeq NM_003656 XM_005265517
HUGO HGNC:1459
OMIM 604998
CCDS CCDS2582
HPRD 05412
IMGT
EMBL AC022382
GenPept
RNA Seq Atlas 8536