Version 5.4
Mus musculus Gene: Myl1
Summary
InnateDB Gene IDBG-163700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myl1
Gene Name myosin, light polypeptide 1
Synonyms AI325107; MLC1f; MLC3f; Mylf
Species Mus musculus
Ensembl Gene ENSMUSG00000061816
Encoded Proteins
IDBP-163702
myosin, light polypeptide 1
IDBP-401159
myosin, light polypeptide 1
IDBP-401158
myosin, light polypeptide 1
IDBP-531940
myosin, light polypeptide 1
IDBP-789511
myosin, light polypeptide 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two non-phosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:66924295-66945404
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000027151 ENSMUSP00000027151
ENSMUST00000119429 ENSMUSP00000112861
ENSMUST00000120415 ENSMUSP00000112880
ENSMUST00000150542
ENSMUST00000160100 ENSMUSP00000125748
ENSMUST00000151328
ENSMUST00000186202 ENSMUSP00000140834
ENSMUST00000186346
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0006936 muscle contraction
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0016459 myosin complex
GO:0030016 myofibril
GO:0043292 contractile fiber
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000168530
View Gene Order
ENSBTAG00000009707
Not yet available
Pathways
NETPATH
REACTOME
REACT_232053
Striated Muscle Contraction pathway
REACT_262759
Muscle contraction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16969
Striated Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
REACT_213099
Muscle contraction pathway
REACT_223821
Striated Muscle Contraction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PWG4 Q6PCW9
UniProt Splice Variant
Entrez Gene 17901
UniGene Mm.391796 Mm.486573
RefSeq XM_006536914 NM_001113387 NM_021285 XM_006495763
OMIM
CCDS CCDS15024 CCDS48284
HPRD
IMGT
MGI ID MGI:97269
MGI Symbol Myl1
EMBL AC124389 AC133187 BC059087
GenPept AAH59087
RNA Seq Atlas 17901

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca