Version 5.4
Homo sapiens Gene: MYL1
Summary
InnateDB Gene IDBG-79939.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYL1
Gene Name myosin, light chain 1, alkali; skeletal, fast
Synonyms MLC1F; MLC3F
Species Homo sapiens
Ensembl Gene ENSG00000168530
Encoded Proteins
IDBP-79941
myosin, light chain 1, alkali; skeletal, fast
IDBP-79943
myosin, light chain 1, alkali; skeletal, fast
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:210290150-210315190
Strand Reverse strand
Band q34
Transcripts
ENST00000341685 ENSP00000343321
ENST00000352451 ENSP00000307280
ENST00000496436
ENST00000484290
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008307 structural constituent of muscle
Biological Process
GO:0006936 muscle contraction
GO:0030049 muscle filament sliding
GO:0060048 cardiac muscle contraction
Cellular Component
GO:0005829 cytosol
GO:0005859 muscle myosin complex
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0043292 contractile fiber
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000061816
View Gene Order
ENSBTAG00000009707
Not yet available
Pathways
NETPATH
REACTOME
REACT_16969
Striated Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.597319
RefSeq NM_079420 NM_079422
HUGO
OMIM
CCDS CCDS2390 CCDS2391
HPRD 01180
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca