Version 5.4
Mus musculus Gene: Nrl
Summary
InnateDB Gene IDBG-163869.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nrl
Gene Name neural retina leucine zipper gene
Synonyms D14H14S46E
Species Mus musculus
Ensembl Gene ENSMUSG00000040632
Encoded Proteins
IDBP-163871
neural retina leucine zipper gene
IDBP-258230
neural retina leucine zipper gene
IDBP-718062
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the basic leucine zipper domain family of transcription factors. The encoded protein is preferentially expressed in the retina and is necessary for rod photoreceptor development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:55518978-55524981
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000062232 ENSMUSP00000054457
ENSMUST00000111404 ENSMUSP00000107035
ENSMUST00000178694 ENSMUSP00000136445
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043522 leucine zipper domain binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007468 regulation of rhodopsin gene expression
GO:0045872 positive regulation of rhodopsin gene expression
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046548 retinal rod cell development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000129535
View Gene Order
ENSBTAG00000001871
Not yet available
Cross-References
SwissProt P54846
TrEMBL Q543Y0
UniProt Splice Variant
Entrez Gene 18185
UniGene
RefSeq NM_001136074 NM_001271916 NM_001271917 NM_008736 XM_006518688
OMIM
CCDS CCDS27113
HPRD
IMGT
MGI ID MGI:102567
MGI Symbol Nrl
EMBL AK044275 AK044316 BC031440 CH466535 L14935
GenPept AAA16843 AAH31440 BAC31849 BAC31863 EDL36292
RNA Seq Atlas 18185

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca