Mus musculus Gene: Sorbs1
Summary
InnateDB Gene IDBG-164596.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sorbs1
Gene Name sorbin and SH3 domain containing 1
Synonyms 2310065E01Rik; 9530001P15Rik; CAP; mKIAA1296; Sh3d5; SH3P12;
Species Mus musculus
Ensembl Gene ENSMUSG00000025006
Encoded Proteins
sorbin and SH3 domain containing 1
sorbin and SH3 domain containing 1
sorbin and SH3 domain containing 1
sorbin and SH3 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000095637:
This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:40295049-40402267
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000099467 ENSMUSP00000097066
ENSMUST00000099466 ENSMUSP00000097065
ENSMUST00000165212 ENSMUSP00000126460
ENSMUST00000165469 ENSMUSP00000125768
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 30 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 30 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0019901 protein kinase binding
Biological Process
GO:0007015 actin filament organization
GO:0008286 insulin receptor signaling pathway
Cellular Component
GO:0001725 stress fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005899 insulin receptor complex
GO:0005925 focal adhesion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
PPAR signaling pathway pathway
Adherens junction pathway
Insulin signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Smooth Muscle Contraction pathway
Muscle contraction pathway
KEGG
PPAR signaling pathway pathway
Adherens junction pathway
Insulin signaling pathway pathway
INOH
PID BIOCARTA
PID NCI
Insulin Pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.210815
RefSeq NM_001034962 NM_001034963 NM_001034964 NM_009166 NM_178362 XM_006526808 XM_006526809 XM_006526810 XM_006526812
OMIM
CCDS CCDS37978 CCDS37979 CCDS37980 CCDS37981
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas