Version 5.4
Mus musculus Gene: Haus8
Summary
InnateDB Gene IDBG-164909.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Haus8
Gene Name 4HAUS augmin-like complex, subunit 8
Synonyms 2410004L22Rik; Hice1
Species Mus musculus
Ensembl Gene ENSMUSG00000035439
Encoded Proteins
IDBP-164911
4HAUS augmin-like complex, subunit 8
IDBP-261053
4HAUS augmin-like complex, subunit 8
IDBP-542370
4HAUS augmin-like complex, subunit 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000131351:
HAUS8 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:71248561-71272934
Strand Reverse strand
Band B3.3
Transcripts
ENSMUST00000035960 ENSMUSP00000040802
ENSMUST00000110071 ENSMUSP00000105698
ENSMUST00000123495 ENSMUSP00000123517
ENSMUST00000157039
ENSMUST00000129455
ENSMUST00000134361
ENSMUST00000144726
ENSMUST00000128833
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0000922 spindle pole
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005874 microtubule
GO:0070652 HAUS complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000131351
View Gene Order
ENSBTAG00000007366
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.27355 Mm.427957
RefSeq NM_001163042 NM_029621 XM_006509779 XM_006509780 XM_006509781
OMIM
CCDS CCDS22389 CCDS52579
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca