Mus musculus Gene: Arap2 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||
InnateDB Gene | IDBG-165165.6 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | Arap2 | ||||||||||||
Gene Name | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | ||||||||||||
Synonyms | |||||||||||||
Species | Mus musculus | ||||||||||||
Ensembl Gene | ENSMUSG00000037999 | ||||||||||||
Encoded Proteins |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
|
||||||||||||
Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000047365:
The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008] |
||||||||||||
Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 5:62602445-62766198 | ||||||||||||
Strand | Reverse strand | ||||||||||||
Band | C3.1 | ||||||||||||
Transcripts |
|
||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||||||
Gene Ontology | |||||||||||||
Molecular Function |
|
||||||||||||
Biological Process |
|
||||||||||||
Cellular Component |
|
||||||||||||
Orthologs | |||||||||||||
Species
Homo sapiens
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||
Pathways | |||||||||||||
NETPATH | |||||||||||||
REACTOME | |||||||||||||
KEGG |
Endocytosis pathway
|
||||||||||||
INOH | |||||||||||||
PID NCI | |||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||
NETPATH | |||||||||||||
REACTOME |
Rho GTPase cycle pathway
Signaling by Rho GTPases pathway
Signal Transduction pathway
|
||||||||||||
KEGG |
Endocytosis pathway
|
||||||||||||
INOH | |||||||||||||
PID NCI |
Arf6 signaling events
|
||||||||||||
Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Mm.244403 Mm.394905 | ||||||||||||
RefSeq | NM_178407 XM_006503830 | ||||||||||||
OMIM | |||||||||||||
CCDS | CCDS51506 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
MGI ID | |||||||||||||
MGI Symbol | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||