Version 5.4
Mus musculus Gene: Itpk1
Summary
InnateDB Gene IDBG-165954.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Itpk1
Gene Name inositol 1,3,4-triphosphate 5/6 kinase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000057963
Encoded Proteins
IDBP-165956
inositol 1,3,4-triphosphate 5/6 kinase
IDBP-709963
IDBP-713408
IDBP-789293
inositol 1,3,4-triphosphate 5/6 kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100605:
Gene Information
Type Protein coding
Genomic Location Chromosome 12:102568582-102704930
Strand Reverse strand
Band E
Transcripts
ENSMUST00000046518 ENSMUSP00000046027
ENSMUST00000178697 ENSMUSP00000137275
ENSMUST00000179417
ENSMUST00000179210 ENSMUSP00000136931
ENSMUST00000191320 ENSMUSP00000139394
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0047325 inositol tetrakisphosphate 1-kinase activity
GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity
GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0032957 inositol trisphosphate metabolic process
Cellular Component
GO:0005622 intracellular
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100605
View Gene Order
ENSBTAG00000009845
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_188937
Metabolism pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
REACT_196482
Synthesis of pyrophosphates in the cytosol pathway
REACT_196476
Inositol phosphate metabolism pathway
REACT_196473
Synthesis of IP3 and IP4 in the cytosol pathway
KEGG
mmu04070
Phosphatidylinositol signaling system pathway
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_150188
Synthesis of pyrophosphates in the cytosol pathway
REACT_150312
Synthesis of IP3 and IP4 in the cytosol pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
REACT_604
Hemostasis pathway
REACT_218731
Synthesis of pyrophosphates in the cytosol pathway
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_212196
Hemostasis pathway
REACT_225102
Synthesis of IP3 and IP4 in the cytosol pathway
REACT_219139
Metabolism pathway
REACT_211106
Inositol phosphate metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
hsa04070
Phosphatidylinositol signaling system pathway
INOH
PID NCI
Cross-References
SwissProt Q8BYN3
TrEMBL J3QNS2 J3QPF8
UniProt Splice Variant
Entrez Gene 217837
UniGene Mm.482192
RefSeq NM_172584
OMIM
CCDS CCDS26121
HPRD
IMGT
MGI ID MGI:2446159
MGI Symbol Itpk1
EMBL AC132315 AC156033 AK038913 BC025917 BC031182 BC056464
GenPept AAH25917 AAH31182 AAH56464 BAC30166
RNA Seq Atlas 217837

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca