Mus musculus Gene: Hnrnph1
Summary
InnateDB Gene IDBG-168689.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hnrnph1
Gene Name heterogeneous nuclear ribonucleoprotein H1
Synonyms AI642080; E430005G16Rik; Hnrnph; Hnrph1;
Species Mus musculus
Ensembl Gene ENSMUSG00000007850
Encoded Proteins
heterogeneous nuclear ribonucleoprotein H1
heterogeneous nuclear ribonucleoprotein H1
heterogeneous nuclear ribonucleoprotein H1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169045:
This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described [provided by RefSeq, Mar 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:50376990-50386528
Strand Forward strand
Band B1.3
Transcripts
ENSMUST00000077817 ENSMUSP00000076989
ENSMUST00000069304 ENSMUSP00000070503
ENSMUST00000109142 ENSMUSP00000104770
ENSMUST00000126737
ENSMUST00000127964
ENSMUST00000123371
ENSMUST00000150153
ENSMUST00000129631
ENSMUST00000133435
ENSMUST00000128220
ENSMUST00000134230
ENSMUST00000141668
ENSMUST00000132715
ENSMUST00000156642
ENSMUST00000150657
ENSMUST00000143301
ENSMUST00000140056
ENSMUST00000151537
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 104 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 14 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 104 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0043484 regulation of RNA splicing
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
mRNA Splicing pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Processing of Capped Intron-Containing Pre-mRNA pathway
mRNA Splicing pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.21740 Mm.436416
RefSeq NM_021510 XM_006533875 XM_006533876 XM_006533877 XM_006533878 XM_006533882
OMIM
CCDS CCDS24634
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas