Version 5.4
Mus musculus Gene: Glrx5
Summary
InnateDB Gene IDBG-168901.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Glrx5
Gene Name glutaredoxin 5 homolog (S. cerevisiae)
Synonyms 2310004O13Rik; 2900070E19Rik; AU020725
Species Mus musculus
Ensembl Gene ENSMUSG00000021102
Encoded Proteins
IDBP-168903
glutaredoxin 5 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182512:
This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:105032689-105040910
Strand Forward strand
Band E
Transcripts
ENSMUST00000021522 ENSMUSP00000021522
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0008150 biological_process
GO:0030097 hemopoiesis
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182512
View Gene Order
ENSBTAG00000013423
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_028419
OMIM
CCDS CCDS26154
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca