Version 5.4
Mus musculus Gene: Ndufb8
Summary
InnateDB Gene IDBG-170017.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufb8
Gene Name NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
Synonyms 2900010I05Rik; AI987932
Species Mus musculus
Ensembl Gene ENSMUSG00000025204
Encoded Proteins
IDBP-170019
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
IDBP-621762
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
IDBP-621764
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
IDBP-621765
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
IDBP-621766
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166136:
Gene Information
Type Protein coding
Genomic Location Chromosome 19:44548572-44555440
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000026222 ENSMUSP00000026222
ENSMUST00000171415 ENSMUSP00000128192
ENSMUST00000168083 ENSMUSP00000132740
ENSMUST00000164543
ENSMUST00000169304 ENSMUSP00000132421
ENSMUST00000167027 ENSMUSP00000130918
ENSMUST00000169181
ENSMUST00000168474
ENSMUST00000166557
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0008150 biological_process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000166136
View Gene Order
ENSBTAG00000000091
Not yet available
Pathways
NETPATH
REACTOME
REACT_189162
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_262523
Respiratory electron transport pathway
REACT_188937
Metabolism pathway
REACT_261922
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
KEGG
mmu00190
Oxidative phosphorylation pathway
mmu05010
Alzheimer's disease pathway
mmu05012
Parkinson's disease pathway
mmu05016
Huntington's disease pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.2060 Mm.458411 Mm.463719
RefSeq NM_026061 XM_006527292
OMIM
CCDS CCDS29851
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca