Version 5.4
Homo sapiens Gene: NDUFB8
Summary
InnateDB Gene IDBG-86575.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDUFB8
Gene Name NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166136
Encoded Proteins
IDBP-86577
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
IDBP-86579
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
IDBP-86581
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
IDBP-597509
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:100523740-100530000
Strand Reverse strand
Band q24.31
Transcripts
ENST00000299166 ENSP00000299166
ENST00000370322 ENSP00000359346
ENST00000370320 ENSP00000359344
ENST00000464651
ENST00000466088
ENST00000528425 ENSP00000434072
ENST00000529437
ENST00000531418
ENST00000531189
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0022904 respiratory electron transport chain
GO:0044237 cellular metabolic process
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005747 mitochondrial respiratory chain complex I
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025204
View Gene Order
ENSBTAG00000000091
Not yet available
Pathways
NETPATH
REACTOME
REACT_22393
Respiratory electron transport pathway
REACT_6305
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
REACT_111083
The citric acid (TCA) cycle and respiratory electron transport pathway
REACT_111217
Metabolism pathway
KEGG
hsa05010
Alzheimer's disease pathway
hsa00190
Oxidative phosphorylation pathway
hsa05012
Parkinson's disease pathway
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.523215
RefSeq NM_001284367 NM_001284368 NM_005004
HUGO
OMIM
CCDS CCDS65916 CCDS65917 CCDS7497
HPRD 11886
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca