Version 5.4
Mus musculus Gene: Arl13b
Summary
InnateDB Gene IDBG-170242.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Arl13b
Gene Name ADP-ribosylation factor-like 13B
Synonyms A530097K21Rik; A930014M17Rik; Arl2l1; C530009C10Rik; hnn
Species Mus musculus
Ensembl Gene ENSMUSG00000022911
Encoded Proteins
IDBP-170244
ADP-ribosylation factor-like 13B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169379:
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:62793685-62847040
Strand Reverse strand
Band C1.3
Transcripts
ENSMUST00000089289 ENSMUSP00000086703
ENSMUST00000141665
ENSMUST00000132902
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0001947 heart looping
GO:0006886 intracellular protein transport
GO:0007224 smoothened signaling pathway
GO:0007264 small GTPase mediated signal transduction
GO:0007368 determination of left/right symmetry
GO:0009953 dorsal/ventral pattern formation
GO:0021532 neural tube patterning
GO:0021830 interneuron migration from the subpallium to the cortex
GO:0021943 formation of radial glial scaffolds
GO:0035058 nonmotile primary cilium assembly
GO:0042384 cilium assembly
GO:0070986 left/right axis specification
Cellular Component
GO:0005622 intracellular
GO:0005929 cilium
GO:0060170 ciliary membrane
GO:0072372 primary cilium
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169379
View Gene Order
ENSBTAG00000005155
Not yet available
Cross-References
SwissProt Q640N2
TrEMBL Q9CUD0
UniProt Splice Variant
Entrez Gene 68146
UniGene Mm.399612 Mm.413151 Mm.96833
RefSeq NM_026577
OMIM
CCDS CCDS28261
HPRD
IMGT
MGI ID MGI:1915396
MGI Symbol Arl13b
EMBL AC154309 AK016794 BC082574 CH466521
GenPept AAH82574 BAB30434 EDK98235
RNA Seq Atlas 68146

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca