Version 5.4
| Mus musculus Gene: Tspan6 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-170366.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Tspan6 | ||||||||
| Gene Name | tetraspanin 6 | ||||||||
| Synonyms | 6720473L21Rik; AI316786; T245; Tm4sf; Tm4sf6; TSPAN-6 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000067377 | ||||||||
| Encoded Proteins |
tetraspanin 6
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000000003:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The protein encoded by this gene is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2 protein. It functions as a negative regulator of retinoic acid-inducible gene I-like receptor-mediated immune signaling via its interaction with the mitochondrial antiviral signaling-centered signalosome. This gene uses alternative polyadenylation sites, and multiple transcript variants result from alternative splicing. [provided by RefSeq, Jul 2013] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome X:133891068-133898429 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | E3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | H3BJJ0 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 56496 | ||||||||
| UniGene | Mm.402063 Mm.406163 Mm.46701 | ||||||||
| RefSeq | NM_019656 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS30387 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1926264 | ||||||||
| MGI Symbol | Tspan6 | ||||||||
| EMBL | AL691421 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 56496 | ||||||||