Version 5.4
Homo sapiens Gene: CLPX
Summary
InnateDB Gene IDBG-17070.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLPX
Gene Name ClpX caseinolytic peptidase X homolog (E. coli)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166855
Encoded Proteins
IDBP-17072
ClpX caseinolytic peptidase X homolog (E. coli)
IDBP-598456
ClpX caseinolytic peptidase X homolog (E. coli)
IDBP-596450
ClpX caseinolytic peptidase X homolog (E. coli)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:65148219-65185342
Strand Reverse strand
Band q22.31
Transcripts
ENST00000300107 ENSP00000300107
ENST00000559152 ENSP00000453461
ENST00000560166
ENST00000558958
ENST00000558103
ENST00000559218 ENSP00000452611
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 18 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004176 ATP-dependent peptidase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008134 transcription factor binding
GO:0016504 peptidase activator activity
GO:0016887 ATPase activity
GO:0046872 metal ion binding
GO:0051082 unfolded protein binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0006457 protein folding
GO:0010952 positive regulation of peptidase activity
GO:0051603 proteolysis involved in cellular protein catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0009368 endopeptidase Clp complex
GO:0009841 mitochondrial endopeptidase Clp complex
GO:0042645 mitochondrial nucleoid
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015357
View Gene Order
ENSBTAG00000008386
Not yet available
Cross-References
SwissProt O76031
TrEMBL A0A024R5X7 H0YK07
UniProt Splice Variant
Entrez Gene 10845
UniGene Hs.609186
RefSeq NM_006660
HUGO HGNC:2088
OMIM 615611
CCDS CCDS10202
HPRD 07478
IMGT
EMBL AC013553 AC068213 AJ006267 AJ276966 AJ276967 AJ276968 AJ276969 AJ276970 AJ276971 AJ276972 AJ276973 AJ276974 AJ276975 AJ276976 AJ276977 AJ276980 AJ276981 AK292316 BC130373 BC136487 CH471082
GenPept AAI30374 AAI36488 BAF85005 CAA06933 CAC01291 EAW77715 EAW77716
RNA Seq Atlas 10845

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca