Version 5.4
| Mus musculus Gene: Ffar1 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-171554.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Ffar1 | ||||||
| Gene Name | free fatty acid receptor 1 | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000044453 | ||||||
| Encoded Proteins |
free fatty acid receptor 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000126266:
This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 7:30860473-30861564 | ||||||
| Strand | Reverse strand | ||||||
| Band | B1 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME |
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
GPCR downstream signaling pathway
Incretin synthesis, secretion, and inactivation pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Integration of energy metabolism pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
Metabolism pathway
Metabolism of proteins pathway
Regulation of insulin secretion pathway
Peptide hormone metabolism pathway
GPCR ligand binding pathway
Free fatty acid receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
Free fatty acids regulate insulin secretion pathway
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Free fatty acid receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Incretin synthesis, secretion, and inactivation pathway
Metabolism of proteins pathway
Free fatty acids regulate insulin secretion pathway
GPCR ligand binding pathway
Metabolism pathway
Peptide hormone metabolism pathway
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| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q76JU9 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 233081 | ||||||
| UniGene | Mm.425422 | ||||||
| RefSeq | NM_194057 | ||||||
| OMIM | |||||||
| CCDS | CCDS21113 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:2684079 | ||||||
| MGI Symbol | Ffar1 | ||||||
| EMBL | AB095745 AF539809 BC132014 BC138099 | ||||||
| GenPept | AAI32015 AAI38100 AAN03478 BAC82555 | ||||||
| RNA Seq Atlas | 233081 | ||||||