Mus musculus Gene: Magoh
Summary
InnateDB Gene IDBG-171992.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Magoh
Gene Name mago-nashi homolog, proliferation-associated (Drosophila)
Synonyms Mago-m; Mos2;
Species Mus musculus
Ensembl Gene ENSMUSG00000028609
Encoded Proteins
mago-nashi homolog, proliferation-associated (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162385:
Drosophila that have mutations in their mago nashi (grandchildless) gene produce progeny with defects in germplasm assembly and germline development. This gene encodes the mammalian mago nashi homolog. In mammals, mRNA expression is not limited to the germ plasm, but is expressed ubiquitously in adult tissues and can be induced by serum stimulation of quiescent fibroblasts. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:107879755-107887424
Strand Forward strand
Band C7
Transcripts
ENSMUST00000030348 ENSMUSP00000030348
ENSMUST00000141376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 165 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 7 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 165 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0006417 regulation of translation
GO:0007292 female gamete generation
GO:0008150 biological_process
GO:0008380 RNA splicing
GO:0051028 mRNA transport
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0035145 exon-exon junction complex
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
Nonsense-Mediated Decay (NMD) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
RNA transport pathway
mRNA surveillance pathway pathway
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
mRNA 3'-end processing pathway
Nonsense-Mediated Decay (NMD) pathway
RNA Polymerase II Transcription Termination pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
mRNA Splicing pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
RNA Polymerase II Transcription pathway
Cleavage of Growing Transcript in the Termination Region pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
RNA Polymerase II Transcription Termination pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Gene Expression pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Nonsense-Mediated Decay (NMD) pathway
KEGG
RNA transport pathway
mRNA surveillance pathway pathway
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.395180 Mm.474588
RefSeq NM_001282737 NM_010760
OMIM
CCDS CCDS18441
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas