Mus musculus Gene: Panx2
Summary
InnateDB Gene IDBG-172246.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Panx2
Gene Name pannexin 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000058441
Encoded Proteins
pannexin 2
pannexin 2
pannexin 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000073150:
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:89059734-89073567
Strand Forward strand
Band E3
Transcripts
ENSMUST00000161372 ENSMUSP00000125514
ENSMUST00000162424 ENSMUSP00000124354
ENSMUST00000159960 ENSMUSP00000124928
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015267 channel activity
GO:0055077 gap junction hemi-channel activity
Biological Process
GO:0002931 response to ischemia
GO:0006811 ion transport
GO:0034214 protein hexamerization
GO:0055085 transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmission across Electrical Synapses pathway
Electric Transmission Across Gap Junctions pathway
Neuronal System pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Electric Transmission Across Gap Junctions pathway
Neuronal System pathway
Transmission across Electrical Synapses pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.397049 Mm.483059
RefSeq NM_001002005 XM_006521139
OMIM
CCDS CCDS49695
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas