Version 5.4
Mus musculus Gene: Fxyd3
Summary
InnateDB Gene IDBG-172317.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fxyd3
Gene Name FXYD domain-containing ion transport regulator 3
Synonyms Mat8
Species Mus musculus
Ensembl Gene ENSMUSG00000057092
Encoded Proteins
IDBP-626571
FXYD domain-containing ion transport regulator 3
IDBP-626574
FXYD domain-containing ion transport regulator 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The encoded protein is a transmembrane protein that functions as a specific regulator of Na,K-ATPase. [provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:31068172-31076704
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000072331
ENSMUST00000167369 ENSMUSP00000130245
ENSMUST00000169313
ENSMUST00000165465
ENSMUST00000165862
ENSMUST00000165265
ENSMUST00000171359 ENSMUSP00000128610
ENSMUST00000169424
ENSMUST00000170456
ENSMUST00000186839
ENSMUST00000186929
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005254 chloride channel activity
GO:0005515 protein binding
GO:0051117 ATPase binding
Biological Process
GO:0006811 ion transport
GO:0034220 ion transmembrane transport
GO:0050790 regulation of catalytic activity
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0034707 chloride channel complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000089356
View Gene Order
ENSBTAG00000040005
Not yet available
Pathways
NETPATH
REACTOME
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_250224
Ion transport by P-type ATPases pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.263847
RefSeq NM_008557
OMIM
CCDS CCDS21125
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca