Version 5.4
Mus musculus Gene: Tdh
Summary
InnateDB Gene IDBG-172747.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tdh
Gene Name L-threonine dehydrogenase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000021953
Encoded Proteins
IDBP-172749
L-threonine dehydrogenase
IDBP-620396
L-threonine dehydrogenase
IDBP-620397
L-threonine dehydrogenase
IDBP-620398
L-threonine dehydrogenase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:63492347-63509092
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000022522 ENSMUSP00000022522
ENSMUST00000168669 ENSMUSP00000132119
ENSMUST00000165776 ENSMUSP00000129206
ENSMUST00000168488 ENSMUSP00000131068
ENSMUST00000170772
ENSMUST00000167685
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0008743 L-threonine 3-dehydrogenase activity
GO:0008831 dTDP-4-dehydrorhamnose reductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662 coenzyme binding
Biological Process
GO:0006567 threonine catabolic process
GO:0006694 steroid biosynthetic process
GO:0009058 biosynthetic process
GO:0019518 L-threonine catabolic process to glycine
GO:0044237 cellular metabolic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
mmu00260
Glycine, serine and threonine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.354229 Mm.455607
RefSeq NM_021480
OMIM
CCDS CCDS27202
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca