InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: ASH2L

Summary

InnateDB Gene

IDBG-17300.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ASH2L

Gene Name

ash2 (absent, small, or homeotic)-like (Drosophila)

Synonyms

ASH2; ASH2L1; ASH2L2; Bre2

Species

Homo sapiens

Ensembl Gene

ENSG00000129691

Encoded Proteins

IDBP-17302

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-366927

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-482895

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-475993

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-479702

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-479527

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-478401

ash2 (absent, small, or homeotic)-like (Drosophila)

IDBP-599755

ash2 (absent, small, or homeotic)-like (Drosophila)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:38105242-38144076

Strand

Forward strand

Band

p11.23

Transcripts

ENST00000343823	ENSP00000340896
ENST00000428278	ENSP00000395310
ENST00000517719	ENSP00000428877
ENST00000517496	ENSP00000430889
ENST00000521652	ENSP00000430259
ENST00000524263
ENST00000522675
ENST00000518186
ENST00000524247	ENSP00000429387
ENST00000521808	ENSP00000427839
ENST00000520079
ENST00000545394	ENSP00000443606

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 117 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	117 [view]
Protein-Protein	111 [view]
Protein-DNA	6 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0042800	histone methyltransferase activity (H3-K4 specific)
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006974	cellular response to DNA damage stimulus
GO:0008284	positive regulation of cell proliferation
GO:0030097	hemopoiesis
GO:0043627	response to estrogen
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051568	histone H3-K4 methylation