Version 5.4
Homo sapiens Gene: KLHL22
Summary
InnateDB Gene IDBG-1734.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KLHL22
Gene Name kelch-like 22 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000099910
Encoded Proteins
IDBP-1753
kelch-like 22 (Drosophila)
IDBP-363228
kelch-like 22 (Drosophila)
IDBP-363246
kelch-like 22 (Drosophila)
IDBP-363250
kelch-like 22 (Drosophila)
IDBP-363253
kelch-like 22 (Drosophila)
IDBP-363257
kelch-like 22 (Drosophila)
IDBP-363260
kelch-like 22 (Drosophila)
IDBP-363261
kelch-like 22 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20441519-20495883
Strand Reverse strand
Band q11.21
Transcripts
ENST00000328879 ENSP00000331682
ENST00000429594 ENSP00000392268
ENST00000451553 ENSP00000400095
ENST00000444967 ENSP00000403999
ENST00000458248 ENSP00000398616
ENST00000443285 ENSP00000397882
ENST00000431430 ENSP00000409092
ENST00000423364 ENSP00000402746
ENST00000487090
ENST00000479601
ENST00000494929
ENST00000470335
ENST00000490556
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0006513 protein monoubiquitination
GO:0007094 mitotic spindle assembly checkpoint
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005827 polar microtubule
GO:0031463 Cul3-RING ubiquitin ligase complex
GO:0072686 mitotic spindle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022750
View Gene Order
ENSBTAG00000020161
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_032775 XM_006724342 XM_006724343
HUGO
OMIM
CCDS CCDS13780
HPRD 07858
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca