Version 5.4
Mus musculus Gene: Aasdh
Summary
InnateDB Gene IDBG-173517.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aasdh
Gene Name aminoadipate-semialdehyde dehydrogenase
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000055923
Encoded Proteins
IDBP-173519
aminoadipate-semialdehyde dehydrogenase
IDBP-400768
aminoadipate-semialdehyde dehydrogenase
IDBP-536244
aminoadipate-semialdehyde dehydrogenase
IDBP-535393
aminoadipate-semialdehyde dehydrogenase
IDBP-539827
aminoadipate-semialdehyde dehydrogenase
IDBP-533241
aminoadipate-semialdehyde dehydrogenase
IDBP-533082
aminoadipate-semialdehyde dehydrogenase
IDBP-539685
aminoadipate-semialdehyde dehydrogenase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The gene product is a cytosolic enzyme involved in the production of alpha-aminoadipic acid from alpha-aminoadipic semialdehyde. It is postulated that this enzyme plays a role in lysine metabolism. There is currently debate regarding this enzyme's putative requirement of pyrroloquinoline quinine as an essential cofactor. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:76873659-76905514
Strand Reverse strand
Band C3.3
Transcripts
ENSMUST00000069709 ENSMUSP00000069279
ENSMUST00000120963 ENSMUSP00000113792
ENSMUST00000123682 ENSMUSP00000121050
ENSMUST00000145022
ENSMUST00000126741 ENSMUSP00000118854
ENSMUST00000149602 ENSMUSP00000117489
ENSMUST00000135697
ENSMUST00000146570 ENSMUSP00000117639
ENSMUST00000123059
ENSMUST00000136080
ENSMUST00000154548
ENSMUST00000135954 ENSMUSP00000120586
ENSMUST00000142450 ENSMUSP00000121556
ENSMUST00000134805
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity
GO:0005524 ATP binding
GO:0016878 acid-thiol ligase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157426
View Gene Order
ENSBTAG00000020583
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.39271
RefSeq NM_173765 XM_006534853 XM_006534855 XM_006534856 XM_006534858 XM_006534859 XM_006534860 XM_006534861
OMIM
CCDS CCDS19366
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca