Mus musculus Gene: Zfyve9
Summary
InnateDB Gene IDBG-173621.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfyve9
Gene Name zinc finger, FYVE domain containing 9
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000034557
Encoded Proteins
zinc finger, FYVE domain containing 9
zinc finger, FYVE domain containing 9
zinc finger, FYVE domain containing 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157077:
This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:108637466-108780798
Strand Reverse strand
Band C7
Transcripts
ENSMUST00000042185 ENSMUSP00000039852
ENSMUST00000106658 ENSMUSP00000102269
ENSMUST00000106657 ENSMUSP00000102268
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005545 1-phosphatidylinositol binding
GO:0046872 metal ion binding
Biological Process
GO:0007183 SMAD protein complex assembly
GO:0007184 SMAD protein import into nucleus
Cellular Component
GO:0031901 early endosome membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
TGF-beta signaling pathway pathway
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TGF_beta_Receptor pathway
REACTOME
KEGG
TGF-beta signaling pathway pathway
Endocytosis pathway
INOH
PID NCI
TGF-beta receptor signaling
Cross-References
SwissProt
TrEMBL A8Y5G5 Q6PDX5 Q80XL0
UniProt Splice Variant
Entrez Gene 230597
UniGene Mm.487102
RefSeq XM_006502988 XM_006502989 NM_183300 XM_006502986 XM_006502987
OMIM
CCDS CCDS38834
HPRD
IMGT
MGI ID MGI:2652838
MGI Symbol Zfyve9
EMBL AL607070 AL626783 AL671909 BC046341 BC058416
GenPept AAH46341 AAH58416
RNA Seq Atlas 230597