Version 5.4
Mus musculus Gene: Ncaph2
Summary
InnateDB Gene IDBG-173751.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ncaph2
Gene Name non-SMC condensin II complex, subunit H2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000008690
Encoded Proteins
IDBP-133015
non-SMC condensin II complex, subunit H2
IDBP-173753
non-SMC condensin II complex, subunit H2
IDBP-173755
non-SMC condensin II complex, subunit H2
IDBP-538107
non-SMC condensin II complex, subunit H2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a component of the condensin-2 complex. The encoded protein may regulate the structure of mitotic chromosomes. Loss of function of this gene disrupts T-cell development. There are two pseudogenes for this gene on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:89355719-89372826
Strand Forward strand
Band E3
Transcripts
ENSMUST00000036987 ENSMUSP00000036900
ENSMUST00000088717 ENSMUSP00000086095
ENSMUST00000074552 ENSMUSP00000074139
ENSMUST00000145259 ENSMUSP00000122118
ENSMUST00000141643
ENSMUST00000123889
ENSMUST00000145793
ENSMUST00000134900
ENSMUST00000147207
ENSMUST00000151523
ENSMUST00000136638
ENSMUST00000140665
ENSMUST00000147733
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0030261 chromosome condensation
GO:0033077 T cell differentiation in thymus
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000025770
View Gene Order
ENSBTAG00000012607
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_196580
Condensation of Prophase Chromosomes pathway
REACT_250557
Mitotic Prophase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172744
Condensation of Prophase Chromosomes pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.143167 Mm.353272 Mm.403652 Mm.469411 Mm.488776
RefSeq NM_001115132 NM_001271600 NM_001271601 NM_025795 XM_006521149 XM_006521150
OMIM
CCDS CCDS49700 CCDS70660 CCDS70661
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca