InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Tymp

Summary

InnateDB Gene

IDBG-173923.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tymp

Gene Name

thymidine phosphorylase

Synonyms

2900072D10Rik; Ecgf1; PD-ECGF; PDECGF; Pdgfec

Species

Mus musculus

Ensembl Gene

ENSMUSG00000022615

Encoded Proteins

IDBP-173925

thymidine phosphorylase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000025708:
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:89371931-89377039

Strand

Reverse strand

Band

Transcripts

ENSMUST00000023285

ENSMUSP00000023285

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004645	phosphorylase activity
GO:0009032	thymidine phosphorylase activity
GO:0016154	pyrimidine-nucleoside phosphorylase activity
GO:0016757	transferase activity, transferring glycosyl groups
GO:0016763	transferase activity, transferring pentosyl groups

Biological Process

GO:0006206	pyrimidine nucleobase metabolic process
GO:0006213	pyrimidine nucleoside metabolic process
GO:0006935	chemotaxis
GO:0008152	metabolic process
GO:0009887	organ morphogenesis