Mus musculus Gene: Tymp
Summary
InnateDB Gene IDBG-173923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tymp
Gene Name thymidine phosphorylase
Synonyms 2900072D10Rik; Ecgf1; PD-ECGF; PDECGF; Pdgfec;
Species Mus musculus
Ensembl Gene ENSMUSG00000022615
Encoded Proteins
thymidine phosphorylase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000025708:
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:89371931-89377039
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000023285 ENSMUSP00000023285
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004645 phosphorylase activity
GO:0009032 thymidine phosphorylase activity
GO:0016154 pyrimidine-nucleoside phosphorylase activity
GO:0016757 transferase activity, transferring glycosyl groups
GO:0016763 transferase activity, transferring pentosyl groups
Biological Process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0006213 pyrimidine nucleoside metabolic process
GO:0006935 chemotaxis
GO:0008152 metabolic process
GO:0009887 organ morphogenesis
Cellular Component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Pyrimidine metabolism pathway
Metabolism pathway
Pyrimidine salvage reactions pathway
Pyrimidine catabolism pathway
Metabolism of nucleotides pathway
KEGG
Pyrimidine metabolism pathway
Drug metabolism pathway
Bladder cancer pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Pyrimidine catabolism pathway
Pyrimidine salvage reactions pathway
Pyrimidine metabolism pathway
Metabolism of nucleotides pathway
Metabolism pathway
KEGG
Pyrimidine metabolism pathway
Drug metabolism pathway
Bladder cancer pathway
INOH
Purine nucleotides nucleosides metabolism pathway
Pyrimidine nucleotides nucleosides metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q99N42
TrEMBL
UniProt Splice Variant
Entrez Gene 72962
UniGene Mm.287977
RefSeq NM_138302
OMIM
CCDS CCDS27747
HPRD
IMGT
MGI ID MGI:1920212
MGI Symbol Tymp
EMBL AB060274
GenPept BAB41208
RNA Seq Atlas 72962