Version 5.4
Mus musculus Gene: Pnoc
Summary
InnateDB Gene IDBG-174253.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pnoc
Gene Name prepronociceptin
Synonyms N/OFQ; N23K; Npnc1; OFQ/N;
Species Mus musculus
Ensembl Gene ENSMUSG00000045731
Encoded Proteins
IDBP-174255
prepronociceptin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168081:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:65400673-65425472
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000059339 ENSMUSP00000054210
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001515 opioid peptide activity
GO:0005515 protein binding
Biological Process
GO:0007218 neuropeptide signaling pathway
GO:0007268 synaptic transmission
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSG00000168081
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000000534
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_250376
G alpha (i) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_19231
G alpha (i) signalling events pathway
REACT_21340
GPCR ligand binding pathway
REACT_219025
Peptide ligand-binding receptors pathway
REACT_205369
Signaling by GPCR pathway
REACT_210568
G alpha (i) signalling events pathway
REACT_214353
Signal Transduction pathway
REACT_214436
GPCR downstream signaling pathway
REACT_220217
GPCR ligand binding pathway
REACT_208412
Class A/1 (Rhodopsin-like receptors) pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q64387
TrEMBL Q543U6 Q99NQ2
UniProt Splice Variant
Entrez Gene 18155
UniGene Mm.16347 Mm.486163
RefSeq NM_001205075 NM_010932
OMIM
CCDS CCDS27213
HPRD
IMGT
MGI ID MGI:105308
MGI Symbol Pnoc
EMBL AK045893 AY011825 BC119372 D50055 D50056 D82866 KF006993 U44027 X97371 X97372 X97373
GenPept AAC52581 AAG38274 AAI19373 AGT80622 BAA08773 BAA08774 BAA11614 BAC32523 CAA66041 CAA66042
RNA Seq Atlas 18155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca