InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Elp3

Summary

InnateDB Gene

IDBG-174279.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Elp3

Gene Name

elongator acetyltransferase complex subunit 3

Synonyms

2610507P14Rik; KAT9

Species

Mus musculus

Ensembl Gene

ENSMUSG00000022031

Encoded Proteins

IDBP-174281

elongation protein 3 homolog (S. cerevisiae)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134014:
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:65530446-65593112

Strand

Reverse strand

Band

Transcripts

ENSMUST00000022609

ENSMUSP00000022609

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003824	catalytic activity
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008080	N-acetyltransferase activity
GO:0008607	phosphorylase kinase regulator activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006368	transcription elongation from RNA polymerase II promoter
GO:0016573	histone acetylation
GO:0030335	positive regulation of cell migration
GO:0045859	regulation of protein kinase activity

Cellular Component

GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0008023	transcription elongation factor complex
GO:0016591	DNA-directed RNA polymerase II, holoenzyme
GO:0033588	Elongator holoenzyme complex