Mus musculus Gene: Elp3
Summary
InnateDB Gene IDBG-174279.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elp3
Gene Name elongator acetyltransferase complex subunit 3
Synonyms 2610507P14Rik; KAT9;
Species Mus musculus
Ensembl Gene ENSMUSG00000022031
Encoded Proteins
elongation protein 3 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134014:
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:65530446-65593112
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000022609 ENSMUSP00000022609
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0004402 histone acetyltransferase activity
GO:0005515 protein binding
GO:0008080 N-acetyltransferase activity
GO:0008607 phosphorylase kinase regulator activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0016573 histone acetylation
GO:0030335 positive regulation of cell migration
GO:0045859 regulation of protein kinase activity
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0008023 transcription elongation factor complex
GO:0016591 DNA-directed RNA polymerase II, holoenzyme
GO:0033588 Elongator holoenzyme complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Chromatin organization pathway
HATs acetylate histones pathway
Chromatin modifying enzymes pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TCR pathway
REACTOME
HATs acetylate histones pathway
Chromatin organization pathway
Chromatin modifying enzymes pathway
Chromatin organization pathway
HATs acetylate histones pathway
Chromatin modifying enzymes pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9CZX0
TrEMBL
UniProt Splice Variant
Entrez Gene 74195
UniGene Mm.474894
RefSeq NM_001253812 NM_028811
OMIM
CCDS CCDS56965
HPRD
IMGT
MGI ID MGI:1921445
MGI Symbol Elp3
EMBL AK012072 AK088457 BC026461 BC057453
GenPept AAH26461 AAH57453 BAB28009 BAC40364
RNA Seq Atlas 74195