InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kcnh7

Summary

InnateDB Gene

IDBG-174319.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kcnh7

Gene Name

potassium voltage-gated channel, subfamily H (eag-related), member 7

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000059742

Encoded Proteins

IDBP-174321

potassium voltage-gated channel, subfamily H (eag-related), member 7

IDBP-255995

potassium voltage-gated channel, subfamily H (eag-related), member 7

IDBP-255997

potassium voltage-gated channel, subfamily H (eag-related), member 7

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184611:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:62693414-63184287

Strand

Reverse strand

Band

C1.3

Transcripts

ENSMUST00000075052	ENSMUSP00000074563
ENSMUST00000112454	ENSMUSP00000108073
ENSMUST00000112452	ENSMUSP00000108071
ENSMUST00000131799

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0005216	ion channel activity
GO:0005242	inward rectifier potassium channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0007165	signal transduction
GO:0007623	circadian rhythm
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0051291	protein heterooligomerization
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0016020	membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000184611

View Gene Order

ENSBTAG00000001899

Not yet available

Pathways

NETPATH

REACTOME

REACT_202800

Potassium Channels pathway

REACT_259290

Neuronal System pathway

REACT_199077

Voltage gated Potassium channels pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_75770

Voltage gated Potassium channels pathway

REACT_13685

Neuronal System pathway

REACT_75908

Potassium Channels pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.242532 Mm.384281 Mm.395919 Mm.406314

RefSeq

NM_133207 XM_006498825

OMIM

CCDS

CCDS38128

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas