InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Hspa1l

Summary

InnateDB Gene

IDBG-175341.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hspa1l

Gene Name

heat shock protein 1-like

Synonyms

Hsc70t; Msh5

Species

Mus musculus

Ensembl Gene

ENSMUSG00000007033

Encoded Proteins

IDBP-175343

heat shock protein 1-like

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204390:
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 17:34972703-34979285

Strand

Forward strand

Band

Transcripts

ENSMUST00000007248

ENSMUSP00000007248

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 94 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	94 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0051082	unfolded protein binding

Biological Process

GO:0000902	cell morphogenesis
GO:0006950	response to stress
GO:0007275	multicellular organismal development
GO:0007283	spermatogenesis
GO:0007339	binding of sperm to zona pellucida
GO:0030154	cell differentiation
GO:0042026	protein refolding

Cellular Component

GO:0002199	zona pellucida receptor complex
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005829	cytosol
GO:0008180	COP9 signalosome
GO:0044297	cell body
GO:0072562	blood microparticle