Mus musculus Gene: Scn7a | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-175377.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | Scn7a | ||||||||||||||||||
Gene Name | sodium channel, voltage-gated, type VII, alpha | ||||||||||||||||||
Synonyms | 1110034K09Rik; AI642000; NaG; Nav2; Nav2.3; Nax; Scn6a | ||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||
Ensembl Gene | ENSMUSG00000034810 | ||||||||||||||||||
Encoded Proteins |
sodium channel, voltage-gated, type VII, alpha
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136546:
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 2:66673425-66784914 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | C1.3 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME |
Interaction between L1 and Ankyrins pathway
L1CAM interactions pathway
Developmental Biology pathway
Axon guidance pathway
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KEGG | |||||||||||||||||||
INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | B1AYL1 Q9QZC3 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 20272 | ||||||||||||||||||
UniGene | Mm.38127 Mm.414399 | ||||||||||||||||||
RefSeq | NM_009135 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS16081 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
MGI ID | MGI:102965 | ||||||||||||||||||
MGI Symbol | Scn7a | ||||||||||||||||||
EMBL | AF190472 AL928623 AL928720 | ||||||||||||||||||
GenPept | AAF07937 | ||||||||||||||||||
RNA Seq Atlas | 20272 | ||||||||||||||||||