Version 5.4
Mus musculus Protein: Scn7a
Summary
InnateDB Protein IDBP-175381.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Scn7a
Protein Name sodium channel, voltage-gated, type VII, alpha
Synonyms 1110034K09Rik; AI642000; NaG; Nav2; Nav2.3; Nax; Scn6a;
Species Mus musculus
Ensembl Protein ENSMUSP00000042405
InnateDB Gene IDBG-175377 (Scn7a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005248 voltage-gated sodium channel activity
GO:0005272 sodium channel activity
GO:0005515 protein binding
Biological Process
GO:0006811 ion transport
GO:0006814 sodium ion transport
GO:0006936 muscle contraction
GO:0019228 neuronal action potential
GO:0034765 regulation of ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0055078 sodium ion homeostasis
GO:0055085 transmembrane transport
GO:0086010 membrane depolarization during action potential
Cellular Component
GO:0001518 voltage-gated sodium channel complex
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0097386 glial cell projection
Protein Structure and Domains
PDB ID MGI:102965
InterPro IPR001696 Voltage gated sodium channel, alpha subunit
IPR005821 Ion transport domain
IPR010526 Sodium ion transport-associated
PFAM PF00520
PF06512
PRINTS PR00170
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9QZC3
UniProt Splice Variant
Entrez Gene 20272
UniGene Mm.414399
RefSeq NP_033161
MGI ID
MGI Symbol Scn7a
OMIM
CCDS CCDS16081
HPRD
IMGT
EMBL AF190472 AL928623 AL928720
GenPept AAF07937

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca