Mus musculus Gene: Cntn1
Summary
InnateDB Gene IDBG-176351.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cntn1
Gene Name contactin 1
Synonyms AW495098; CNTN; F3cam;
Species Mus musculus
Ensembl Gene ENSMUSG00000055022
Encoded Proteins
contactin 1
contactin 1
contactin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000018236:
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:92051165-92341967
Strand Forward strand
Band E3
Transcripts
ENSMUST00000000109 ENSMUSP00000000109
ENSMUST00000068378 ENSMUSP00000067842
ENSMUST00000141187
ENSMUST00000169825 ENSMUSP00000133063
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001948 glycoprotein binding
GO:0005515 protein binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007155 cell adhesion
GO:0007219 Notch signaling pathway
GO:0010628 positive regulation of gene expression
GO:0010765 positive regulation of sodium ion transport
GO:0010976 positive regulation of neuron projection development
GO:0021549 cerebellum development
GO:0031175 neuron projection development
Cellular Component
GO:0005886 plasma membrane
GO:0031225 anchored component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Disease pathway
Signaling by NOTCH1 pathway
Activated NOTCH1 Transmits Signal to the Nucleus pathway
Signaling by NOTCH2 pathway
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
Signaling by NOTCH1 in Cancer pathway
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
FBXW7 Mutants and NOTCH1 in Cancer pathway
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
Axon guidance pathway
L1CAM interactions pathway
Developmental Biology pathway
Neurofascin interactions pathway
Signal Transduction pathway
Signaling by NOTCH pathway
KEGG
Cell adhesion molecules (CAMs) pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
Notch pathway
REACTOME
Developmental Biology pathway
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant pathway
Signaling by NOTCH1 in Cancer pathway
NOTCH2 Activation and Transmission of Signal to the Nucleus pathway
Axon guidance pathway
FBXW7 Mutants and NOTCH1 in Cancer pathway
Signal Transduction pathway
Signaling by NOTCH2 pathway
Neurofascin interactions pathway
Signaling by NOTCH1 PEST Domain Mutants in Cancer pathway
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer pathway
Signaling by NOTCH pathway
L1CAM interactions pathway
Signaling by NOTCH1 pathway
Signaling by NOTCH1 HD Domain Mutants in Cancer pathway
Activated NOTCH1 Transmits Signal to the Nucleus pathway
Disease pathway
KEGG
Cell adhesion molecules (CAMs) pathway
INOH
PID BIOCARTA
PID NCI
Notch signaling pathway
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.401243 Mm.470343 Mm.4911
RefSeq NM_001159647 NM_001159648 NM_007727
OMIM
CCDS CCDS27763
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas