Mus musculus Gene: Klk5
Summary
InnateDB Gene IDBG-177655.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klk5
Gene Name kallikrein related-peptidase 5
Synonyms 1110030O19Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000074155
Encoded Proteins
kallikrein related-peptidase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167754:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:43842269-43851181
Strand Forward strand
Band B3
Transcripts
ENSMUST00000048444 ENSMUSP00000049339
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005515 protein binding
Biological Process
GO:0006508 proteolysis
GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway
Cellular Component
GO:0097209 epidermal lamellar body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL Q9D140
UniProt Splice Variant
Entrez Gene 68668
UniGene Mm.458122
RefSeq NM_026806 XM_006541150 XM_006541151 XM_006541152
OMIM
CCDS CCDS21185
HPRD
IMGT
MGI ID MGI:1915918
MGI Symbol Klk5
EMBL AC134858 AK003996 BC139475 BC139478
GenPept AAI39476 AAI39479 BAB23113
RNA Seq Atlas 68668