Mus musculus Gene: Gc
Summary
InnateDB Gene IDBG-177825.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gc
Gene Name group specific component
Synonyms DBP; VDB;
Species Mus musculus
Ensembl Gene ENSMUSG00000035540
Encoded Proteins
group specific component
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145321:
The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:89417511-89457898
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000049209 ENSMUSP00000046636
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0051183 vitamin transporter activity
GO:1902118 calcidiol binding
Biological Process
GO:0042359 vitamin D metabolic process
GO:0051180 vitamin transport
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Vitamin D (calciferol) metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism of steroid hormones and vitamin D pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Metabolism of lipids and lipoproteins pathway
Metabolism of steroid hormones and vitamin D pathway
Vitamin D (calciferol) metabolism pathway
Metabolism pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.196595 Mm.471796
RefSeq NM_008096
OMIM
CCDS CCDS19407
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas