Mus musculus Gene: Tubb5
Summary
InnateDB Gene IDBG-179144.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tubb5
Gene Name tubulin, beta 5 class I
Synonyms AA408537; AI596182; B130022C14Rik; M(beta)5;
Species Mus musculus
Ensembl Gene ENSMUSG00000001525
Encoded Proteins
tubulin, beta 5
tubulin, beta 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196230:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:35833921-35838306
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000001566 ENSMUSP00000001566
ENSMUST00000134978 ENSMUSP00000134598
ENSMUST00000156050
ENSMUST00000173253
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 155 interaction(s) predicted by orthology.
Experimentally validated
Total 37 [view]
Protein-Protein 37 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 155 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019904 protein domain specific binding
GO:0032403 protein complex binding
GO:0032794 GTPase activating protein binding
GO:0042288 MHC class I protein binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006457 protein folding
GO:0007017 microtubule-based process
GO:0009987 cellular process
GO:0051225 spindle assembly
GO:0051258 protein polymerization
Cellular Component
GO:0005634 nucleus
GO:0005641 nuclear envelope lumen
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0043234 protein complex
GO:0044297 cell body
GO:0045298 tubulin complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Recruitment of mitotic centrosome proteins and complexes pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Cell Cycle pathway
Mitotic G2-G2/M phases pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Centrosome maturation pathway
KEGG
Phagosome pathway
Gap junction pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TCR pathway
REACTOME
Loss of Nlp from mitotic centrosomes pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Mitotic G2-G2/M phases pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Mitotic G2-G2/M phases pathway
Cell Cycle pathway
Loss of proteins required for interphase microtubule organization√?¬†from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Centrosome maturation pathway
KEGG
Phagosome pathway
Gap junction pathway
Pathogenic Escherichia coli infection pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL G3UZR1
UniProt Splice Variant
Entrez Gene 22154
UniGene Mm.273538 Mm.472638 Mm.490591
RefSeq NM_011655
OMIM
CCDS CCDS28706
HPRD
IMGT
MGI ID MGI:107812
MGI Symbol Tubb5
EMBL CR974451
GenPept
RNA Seq Atlas 22154