Version 5.4
Mus musculus Gene: Rcbtb2
Summary
InnateDB Gene IDBG-179741.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rcbtb2
Gene Name regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Synonyms 2610028E02Rik; 2810420M18Rik; AI448345; AW240694; Chc1l; RC/BTB2
Species Mus musculus
Ensembl Gene ENSMUSG00000022106
Encoded Proteins
IDBP-179743
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-259160
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620455
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620456
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620457
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620462
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620463
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620465
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620466
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620468
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620469
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620470
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620471
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620472
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620473
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620474
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620475
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620476
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620477
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
IDBP-620478
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136161:
This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran. [provided by RefSeq, Jul 2008]
This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:73123037-73207843
Strand Forward strand
Band D3
Transcripts
ENSMUST00000022702 ENSMUSP00000022702
ENSMUST00000110952 ENSMUSP00000106577
ENSMUST00000163339 ENSMUSP00000131374
ENSMUST00000163650
ENSMUST00000171070 ENSMUSP00000132723
ENSMUST00000170370 ENSMUSP00000130732
ENSMUST00000164822 ENSMUSP00000131588
ENSMUST00000165429 ENSMUSP00000127258
ENSMUST00000163546
ENSMUST00000170368 ENSMUSP00000126276
ENSMUST00000171767 ENSMUSP00000127397
ENSMUST00000163533 ENSMUSP00000130828
ENSMUST00000171163
ENSMUST00000165334
ENSMUST00000170677 ENSMUSP00000126510
ENSMUST00000167401 ENSMUSP00000128221
ENSMUST00000169513 ENSMUSP00000128579
ENSMUST00000165646
ENSMUST00000165727 ENSMUSP00000128479
ENSMUST00000165567 ENSMUSP00000130240
ENSMUST00000167021 ENSMUSP00000131496
ENSMUST00000164298 ENSMUSP00000126651
ENSMUST00000163797 ENSMUSP00000132125
ENSMUST00000166875 ENSMUSP00000130168
ENSMUST00000170278
ENSMUST00000169479 ENSMUSP00000126898
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0001669 acrosomal vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000136161
View Gene Order
ENSBTAG00000006647
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.280068 Mm.482968
RefSeq NM_001170694 NM_134083 XM_006518382 XM_006518383 XM_006518384 XM_006518385 XM_006518386
OMIM
CCDS CCDS27266
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca