Mus musculus Gene: Wrb
InnateDB Gene IDBG-179806.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wrb
Gene Name tryptophan rich basic protein
Synonyms 5530402J05Rik; C030018G21Rik; Chd5
Species Mus musculus
Ensembl Gene ENSMUSG00000023147
Encoded Proteins
tryptophan rich basic protein
tryptophan rich basic protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182093:
This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:96145407-96157852
Strand Forward strand
Band C4
ENSMUST00000023913 ENSMUSP00000023913
ENSMUST00000135448 ENSMUSP00000122059
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005730 nucleolus
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt Q8K0D7
UniProt Splice Variant
Entrez Gene 71446
UniGene Mm.255063 Mm.417596
RefSeq NM_207301
MGI ID MGI:2136882
MGI Symbol Wrb
EMBL AK172079 BC031769
GenPept AAH31769 BAE42815
RNA Seq Atlas 71446