Bos taurus Gene: WRB
Summary
InnateDB Gene IDBG-639175.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WRB
Gene Name Tail-anchored protein insertion receptor WRB
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013629
Encoded Proteins
Tryptophan-rich protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182093:
This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in adult and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:140944009-140958949
Strand Forward strand
Band
Transcripts
ENSBTAT00000018116 ENSBTAP00000018116
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q3SZ26
TrEMBL
UniProt Splice Variant
Entrez Gene 509739
UniGene Bt.49103
RefSeq NM_001034359
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103216
GenPept AAI03217
RNA Seq Atlas 509739