Version 5.4
Homo sapiens Gene: CD69
Summary
InnateDB Gene IDBG-18077.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD69
Gene Name CD69 molecule
Synonyms AIM; BL-AC/P26; CLEC2C; EA1; GP32/28; MLR-3
Species Homo sapiens
Ensembl Gene ENSG00000110848
Encoded Proteins
IDBP-18079
CD69 molecule
IDBP-588799
CD69 molecule
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:9752486-9760901
Strand Reverse strand
Band p13.31
Transcripts
ENST00000228434 ENSP00000228434
ENST00000416624
ENST00000536709 ENSP00000442597
ENST00000543147
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 2 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0005509 calcium ion binding
GO:0030246 carbohydrate binding
Biological Process
GO:0007165 signal transduction
GO:0035690 cellular response to drug
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030156
View Gene Order
ENSBTAG00000002135
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.208854 Hs.706997
RefSeq NM_001781
HUGO
OMIM
CCDS CCDS8604
HPRD 00119
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca