InnateDB Protein
|
IDBP-18079.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
CD69
|
Protein Name
|
CD69 molecule
|
Synonyms
|
AIM; BL-AC/P26; CLEC2C; EA1; GP32/28; MLR-3;
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000228434
|
InnateDB Gene
|
IDBG-18077 (CD69)
|
Protein Structure
|
|
Function |
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
|
Subcellular Localization |
Membrane; Single-pass type II membrane protein.
|
Disease Associations |
|
Tissue Specificity |
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
4
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR001304
C-type lectin
IPR008646
Herpesvirus UL45-like
IPR016187
C-type lectin fold
|
PFAM |
PF00059
PF05473
|
PRINTS |
|
PIRSF |
|
SMART |
SM00034
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q07108
|
PhosphoSite |
PhosphoSite-Q07108
|
TrEMBL |
Q6LAB3
|
UniProt Splice Variant |
|
Entrez Gene |
969
|
UniGene |
Hs.706997
|
RefSeq |
NP_001772
|
HUGO |
HGNC:1694
|
OMIM |
107273
|
CCDS |
CCDS8604
|
HPRD |
00119
|
IMGT |
|
EMBL |
AC007068
AK291869
AK303174
AY238518
BC007037
CH471094
L07555
Z22576
Z30426
Z30427
Z30428
Z30429
Z30430
Z38109
|
GenPept |
AAB46359
AAH07037
AAO63584
BAF84558
BAG64271
CAA80298
CAA83017
CAA86225
EAW96122
EAW96123
|
|
|