Mus musculus Gene: Ces5a
Summary
InnateDB Gene IDBG-181099.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ces5a
Gene Name carboxylesterase 5A
Synonyms 1700081L16Rik; 1700122C07Rik; BB081581; cauxin; Ces7; Gm503;
Species Mus musculus
Ensembl Gene ENSMUSG00000058019
Encoded Proteins
carboxylesterase 5A
carboxylesterase 5A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159398:
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES5, is predominantly expressed in peripheral tissues, including brain, kidney, lung and testis. It encodes a secreted enzyme. Because of high levels in the urine of male domestic cats, this enzyme is also called cauxin (carboxylesterase-like urinary excreted protein). The enzyme functions in regulating the production of a pheromone precursor and may contribute to lipid and cholesterol transfer processes within male reproductive fluids. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:93499213-93535707
Strand Reverse strand
Band C5
Transcripts
ENSMUST00000080391 ENSMUSP00000079254
ENSMUST00000077816 ENSMUSP00000076988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.390064
RefSeq NM_001003951 XM_006531320 XM_006531322
OMIM
CCDS
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas