Version 5.4
Mus musculus Gene: Hoxd1
Summary
InnateDB Gene IDBG-181282.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hoxd1
Gene Name homeobox D1
Synonyms Hox-4.9
Species Mus musculus
Ensembl Gene ENSMUSG00000042448
Encoded Proteins
IDBP-181284
homeobox D1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128645:
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:74762980-74765142
Strand Forward strand
Band C3
Transcripts
ENSMUST00000047793 ENSMUSP00000043078
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 1 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019233 sensory perception of pain
GO:0030182 neuron differentiation
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000128645
View Gene Order
ENSBTAG00000015840
Not yet available
Cross-References
SwissProt Q01822
TrEMBL
UniProt Splice Variant
Entrez Gene 15429
UniGene Mm.407433 Mm.4932
RefSeq NM_010467
OMIM
CCDS CCDS16147
HPRD
IMGT
MGI ID MGI:96201
MGI Symbol Hoxd1
EMBL AL928733 BC120537 BC120539 CH466519 M87802 X60034
GenPept AAA37853 AAI20538 AAI20540 CAA42637 EDL27181
RNA Seq Atlas 15429

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca