Homo sapiens Gene: HOXD1
Summary
InnateDB Gene IDBG-75776.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HOXD1
Gene Name homeobox D1
Synonyms Hox-4.7; HOX4; HOX4G;
Species Homo sapiens
Ensembl Gene ENSG00000128645
Encoded Proteins
homeobox D1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. This nuclear protein functions as a sequence-specific transcription factor that is involved in differentiation and limb development. Mutations in this gene have been associated with severe developmental defects on the anterior-posterior (a-p) limb axis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:176188579-176190907
Strand Forward strand
Band q31.1
Transcripts
ENST00000331462 ENSP00000328598
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019233 sensory perception of pain
GO:0030182 neuron differentiation
GO:0048706 embryonic skeletal system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.608223 Hs.83465
RefSeq NM_024501
HUGO
OMIM
CCDS CCDS2271
HPRD 00870
IMGT
EMBL
GenPept
RNA Seq Atlas