Mus musculus Gene: Ndufaf2
Summary
InnateDB Gene IDBG-181431.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufaf2
Gene Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
Synonyms 1810058I14Rik; C86051; mimitin; Ndufa12l;
Species Mus musculus
Ensembl Gene ENSMUSG00000068184
Encoded Proteins
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164182:
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:108052590-108158625
Strand Reverse strand
Band D2.1
Transcripts
ENSMUST00000163558 ENSMUSP00000130532
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0022904 respiratory electron transport chain
GO:0045333 cellular respiration
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0072593 reactive oxygen species metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Validated targets of C-MYC transcriptional activation
Cross-References
SwissProt Q59J78
TrEMBL
UniProt Splice Variant
Entrez Gene 75597
UniGene
RefSeq NM_001127346
OMIM
CCDS CCDS49357
HPRD
IMGT
MGI ID MGI:1922847
MGI Symbol Ndufaf2
EMBL AB183434 AY262012 BC116975 BC116977
GenPept AAI16976 AAI16978 AAP33449 BAD91206
RNA Seq Atlas 75597