Version 5.4
Mus musculus Gene: Tsc22d1
Summary
InnateDB Gene IDBG-181552.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tsc22d1
Gene Name TSC22 domain family, member 1
Synonyms AA589566; AW105905; Egr5; Tgfb1i4; Tsc; TSC-22; Tsc22
Species Mus musculus
Ensembl Gene ENSMUSG00000022010
Encoded Proteins
IDBP-142024
TSC22 domain family, member 1
IDBP-181556
TSC22 domain family, member 1
IDBP-181560
TSC22 domain family, member 1
IDBP-259326
TSC22 domain family, member 1
IDBP-717554
IDBP-718070
IDBP-717309
IDBP-717322
IDBP-718693
IDBP-717037
IDBP-717673
IDBP-717869
IDBP-715829
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102804:
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:76414961-76507765
Strand Forward strand
Band D3
Transcripts
ENSMUST00000101618 ENSMUSP00000099140
ENSMUST00000048371 ENSMUSP00000044517
ENSMUST00000022587 ENSMUSP00000022587
ENSMUST00000110888 ENSMUSP00000106513
ENSMUST00000142683 ENSMUSP00000135493
ENSMUST00000140251 ENSMUSP00000135806
ENSMUST00000134109 ENSMUSP00000135146
ENSMUST00000133224 ENSMUSP00000135561
ENSMUST00000177471 ENSMUSP00000134792
ENSMUST00000177333
ENSMUST00000175655
ENSMUST00000176886 ENSMUSP00000135202
ENSMUST00000177207 ENSMUSP00000135296
ENSMUST00000175984 ENSMUSP00000135307
ENSMUST00000175811
ENSMUST00000176581 ENSMUSP00000135789
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 149 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 149 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0043065 positive regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000102804
View Gene Order
Cross-References
SwissProt
TrEMBL H3BLI9
UniProt Splice Variant
Entrez Gene 21807
UniGene Mm.153272 Mm.308763 Mm.440970 Mm.489096
RefSeq NM_001177751 NM_009366 NM_207652 XM_006518803 XM_006518804 XM_006518805
OMIM
CCDS CCDS27285 CCDS27286 CCDS49545
HPRD
IMGT
MGI ID MGI:109127
MGI Symbol Tsc22d1
EMBL AC134842 AC142266
GenPept
RNA Seq Atlas 21807

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca