Version 5.4
Mus musculus Gene: Cx3cl1
Summary
InnateDB Gene IDBG-182616.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cx3cl1
Gene Name chemokine (C-X3-C motif) ligand 1
Synonyms AB030188; ABCD-3; AI848747; CX3C; Cxc3; D8Bwg0439e; Scyd1
Species Mus musculus
Ensembl Gene ENSMUSG00000031778
Encoded Proteins
IDBP-182618
chemokine (C-X3-C motif) ligand 1
IDBP-540678
chemokine (C-X3-C motif) ligand 1
IDBP-541711
chemokine (C-X3-C motif) ligand 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000006210:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:94772009-94782423
Strand Forward strand
Band C5
Transcripts
ENSMUST00000034230 ENSMUSP00000034230
ENSMUST00000151783
ENSMUST00000135970 ENSMUSP00000117632
ENSMUST00000150307 ENSMUSP00000123538
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008009 chemokine activity
Biological Process
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0019221 cytokine-mediated signaling pathway
GO:0030593 neutrophil chemotaxis
GO:0032914 positive regulation of transforming growth factor beta1 production
GO:0042060 wound healing
GO:0045766 positive regulation of angiogenesis
GO:0048246 macrophage chemotaxis
GO:0048247 lymphocyte chemotaxis
GO:0050729 positive regulation of inflammatory response
GO:0051041 positive regulation of calcium-independent cell-cell adhesion
GO:0060055 angiogenesis involved in wound healing
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000006210
View Gene Order
ENSBTAG00000024869
Not yet available
Pathways
NETPATH
REACTOME
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_230248
Chemokine receptors bind chemokines pathway
REACT_188257
Signal Transduction pathway
KEGG
mmu04060
Cytokine-cytokine receptor interaction pathway
mmu04062
Chemokine signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15344
Chemokine receptors bind chemokines pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04060
Cytokine-cytokine receptor interaction pathway
hsa04062
Chemokine signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.103711 Mm.397008 Mm.475039
RefSeq NM_009142
OMIM
CCDS CCDS22548
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca