Mus musculus Gene: Fbxl14
InnateDB Gene IDBG-182726.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxl14
Gene Name F-box and leucine-rich repeat protein 14
Synonyms AW322056; Fbx14l
Species Mus musculus
Ensembl Gene ENSMUSG00000030019
Encoded Proteins
F-box and leucine-rich repeat protein 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171823:
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:119479668-119482630
Strand Forward strand
Band F1
ENSMUST00000032094 ENSMUSP00000032094
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt Q8BID8
UniProt Splice Variant
Entrez Gene 101358
UniGene Mm.125477 Mm.407623 Mm.440694 Mm.448356
RefSeq NM_133940
MGI ID MGI:2141676
MGI Symbol Fbxl14
EMBL AF467463 AK084506 AK155154 BC006913 BC021329
GenPept AAH06913 AAH21329 AAL75967 BAC39201 BAE33081
RNA Seq Atlas 101358