Version 5.4
Mus musculus Gene: Fbxl14
Summary
InnateDB Gene IDBG-182726.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fbxl14
Gene Name F-box and leucine-rich repeat protein 14
Synonyms AW322056; Fbx14l
Species Mus musculus
Ensembl Gene ENSMUSG00000030019
Encoded Proteins
IDBP-182728
F-box and leucine-rich repeat protein 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171823:
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:119479668-119482630
Strand Forward strand
Band F1
Transcripts
ENSMUST00000032094 ENSMUSP00000032094
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000171823
View Gene Order
ENSBTAG00000007786
Not yet available
Cross-References
SwissProt Q8BID8
TrEMBL
UniProt Splice Variant
Entrez Gene 101358
UniGene Mm.125477 Mm.407623 Mm.440694 Mm.448356
RefSeq NM_133940
OMIM
CCDS CCDS20475
HPRD
IMGT
MGI ID MGI:2141676
MGI Symbol Fbxl14
EMBL AF467463 AK084506 AK155154 BC006913 BC021329
GenPept AAH06913 AAH21329 AAL75967 BAC39201 BAE33081
RNA Seq Atlas 101358

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca