Mus musculus Gene: Aqp5
Summary
InnateDB Gene IDBG-183403.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp5
Gene Name aquaporin 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000044217
Encoded Proteins
aquaporin 5
aquaporin 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161798:
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:99590849-99594829
Strand Forward strand
Band F1
Transcripts
ENSMUST00000088200 ENSMUSP00000085530
ENSMUST00000169082 ENSMUSP00000127611
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0015250 water channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0015670 carbon dioxide transport
GO:0030157 pancreatic juice secretion
GO:0042476 odontogenesis
GO:0046541 saliva secretion
GO:0048593 camera-type eye morphogenesis
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0009925 basal plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Aquaporin-mediated transport pathway
Passive transport by Aquaporins pathway
Transmembrane transport of small molecules pathway
KEGG
Salivary secretion pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Passive transport by Aquaporins pathway
Aquaporin-mediated transport pathway
KEGG
Salivary secretion pathway
INOH
PID BIOCARTA
PID NCI
Stabilization and expansion of the E-cadherin adherens junction
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.45580
RefSeq NM_009701
OMIM
CCDS CCDS27823
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas